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Advancing technology gives rise to newer methods of healing. In the field of dentistry, the major development is taking place in methods of regenerating gum tissue. Gum tissue is vital in supporting teeth and holding them in place.
The latest development by Scientists at the University of Michigan, for regenerating gum tissue is a technique that uses gene delivery. This method of gene delivery looks safe and does not seem to pose any hazards for regenerating gum tissue that supports teeth. According to William Giannobile, a professor at the U-M School of Dentistry, there still remain many issues that revolve around concern for safety of the patient undergoing gene therapy, though this form of therapy is accepted widely as a method of treatment and healing.
This concern for safety was highlighted in the early stages of its development a number of years ago, when a teenager undergoing gene therapy died after the administration of adenovirus during a gene therapy clinical trial at the University of Pennsylvania.
Gene therapy versus U-M therapy
When he compared gene therapy to U-M therapy, Professor Giannobile said that both therapies use adenovirus but in U-M therapy, the dosage is much lower and treatment is in the form of a local application, quite like a paste which is applied directly on the tissue during surgery; as opposed to gene therapy where the genes are injected directly in the blood vessels which allows adenovirus to travel in the blood stream and this may at times result in unexpected developments which can sometimes be fatal. The U-M method is more of a topical method where the adenovirus is controlled in the localised area and is not allowed to spread throughout the body. This approach lessens concerns of saftey and about negative reactions that may occur within the body.
Professor Giannobile, who has an appointment at the U-M College of Engineering’s Department of Biomedical Engineering and also directs the Michigan Center for Oral Health Research, explained that the teenager died, as the adenovirus got into his bloodstream and he reacted adversely to it. It was tragic.
He said that in the first study of periodontal disease therapy, it was demonstrated the that distribution of these genes was very safe. He also said that it could be used in the clinic for clinical application. He said that their study does not address all the safety concerns, but that safety was surely a very important concern to the field. (The success of using this treatment will surely depend on its safety factor.) The U-M method of treatment shows great potential in clinical treatment of Periodontal disease and diabetic wounds. He pointed out that that this could be due to the fact that both these diseases are a result of a “defective healing environment.”
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Naperville Magazine is conducting their third annual “Best of Naperville Magazine Awards” You vote, You decide, and they will publish the winners in the August 2011 issue. There are forty categories to vote for, covering everything from best burger to best dentist. Remember, you choose the winner! Each person is able to cast 10 votes.
If you LOVE your dentist/orthodontist
- Log on to www.napervillemagazine.com
- In the upper right corner click – “Click here to vote”
- In the bottom left of the next screen click “Click here to login or register”
- Login OR Click “Create new account”
- You will be asked to create your own personal UserName and Password
- Enter username, email address, and password then click on “Create New Account”
- On next screen Click “Click here to vote”
- All 40 categories will list
- Go to Best Dentist/Practice and TYPE: Naperville Dental/Innovative Orthodontics
- Click on Submit
- Vote 10 times
THANK YOU for your support!!!
Also, congratulations to Naperville Magazine! The Tribune company has acquired the magazine which is great for them and area businesses!!! Way To GO!
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Fox News reported on a study revealed that the longer teenagers spend glued to the screen, the greater the impact on their dental hygiene.
We’re so proud of BOTH schools for participating and for doing such an amazing job on the windows for the contest! Good Luck to all these wonderful future artists!!
CLICK: Naperville Sun
Aspiring artists from Naperville North edged out the talented team from Neuqua Valley in the annual holiday window competition sponsored by Innovative Orthodontic Centers and Naperville Dental Specialists.
“It was a difficult decision to select the winner this year,” said Dr. Anthony LaVacca. “Both windows demonstrated amazing artistic talent, and both truly have the Christmas spirit.”
For its festive mural — complete with a set of pearly whites and Ike the Bear — Naperville North’s art club received a $500 prize. Neuqua Valley art club members will find plenty of uses for their $200 runner-up award.